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Through a comparative analysis, this systematic review aims to compare the efficacy of tirzepatide and semaglutide in facilitating weight loss and their respective safety profiles

It represents the next generation of weight loss medications because it activates both GLP-1 and GIP receptors, a dual mechanism that clinical trials showed produces even greater weight loss than semaglutide alone

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Cells were cultured at 37C with 5% CO 2 in DMEM supplemented with 10% FBS, 100 U/ml penicillin, 100 g/ml streptomycin and 75 mol/l -mercaptoethanol