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5, in Nature Medicine seems to back up the FDAs preliminary findings.[1] Rong Xu, PhD, a professor of biomedical informatics and director of the Center for AI in Drug Discovery at Case Western Reserve University, and colleagues examined data from more than 240,000 overweight or obese patients prescribed either semaglutide or non-GLP-1 receptor agonist anti-obesity medications

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Archived from the original on March 29, 2026

In practical terms, patients on tirzepatide often experience stronger appetite reduction, fewer cravings, and more significant weight loss over a comparable treatment period