Il tessuto adiposo, soprattutto quello viscerale che si deposita intorno a fegato, reni, intestino e cuore, si comporta come un vero organo endocrino e infiammatorio
NICE Technology Appraisal (TA) 870 recommends tirzepatide as an option for treating type 2 diabetes in adults with inadequate glycaemic control, specifically as part of a triple therapy regimen or as a dual therapy with insulin when certain criteria are met
The hyperpigmentation associated with melasma and post-inflammatory hyperpigmentation may be worsened by laser treatment, as the heat and energy can cause the pigment itself to become further entrenched in the skin
In adverse event reports, alogliptin was associated with 3 cases of biliary malignancies, linagliptin with 9 cases, and their 95%CI for ROR and EBGM05 exceeded the signal detection thresholds, indicating a possible statistically significant correlation
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doi: 10.1016/j.medcli.2017.01.034