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This route loses 6075% of active peptide to hepatic first-pass metabolism and renal clearance before any meaningful dermal concentration is achieved

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Chin J Birth Health Heredity 18(01):7071 Polanska K, Krol A, Sobala W, Gromadzinska J, Brodzka R, Calamandrei G, Chiarotti F, Wasowicz W, Hanke W (2016) Selenium status during pregnancy and child psychomotor development-polish mother and child cohort study

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