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Allowing injected areas to reach room temperature before administration, using a fresh needle with each injection, and maintaining proper skin preparation with alcohol wipes reduce tissue damage

The GLP-1 injection site guide and GLP-1 injection technique guide cover the fundamentals

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There are however no specific recommendations for these adjustments, currently mainly based on expert opinions.29 A series of clinical considerations and expert opinions on the insulin regimen employed are provided by the authors of a comprehensive revision in which a multiple-daily-injection regime associated with long-acting and short-acting insulin on meal times is preferred both to avoid glycemic variability related to dialysate dextrose and hypoglycemia episodes