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For NAION, the risk appears higher with GLP-1 users who are obese and diabetic, though the available early data is incomplete. He believes the risk may be higher in patients with small optic nerve cups, sometimes described as a disc at risk. Regarding neovascular age-related macular degeneration, he said signals exist, though causality has not been established

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Stage 1: Stage 1 indicates that the melanoma is still localized, meaning it is only present in one section

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J Physiol Pharmacol 60:191196 Brooks J (2005) Epidemiology of injuries in English professional rugby union: part 2 training injuries