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Reply to comment on the effect of semaglutide and GLP-1 RAs on risk of nonarteritic anterior ischemic optic neuropathy [published online ahead of print June 20, 2025]

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The study will use

The initial mechanical stimulus by the pressure peaks induces cellular changes through mechanotransduction, mobilizing the extracellular matrix

Mazdutide is a synthetic peptide and dual hormone receptor agonist that activates both the GLP-1 (glucagon-like peptide-1) receptor and the glucagon receptor