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Researchers are expected to operate within their own institutional ethics, Control of Substances Hazardous to Health (COSHH), and biosafety frameworks

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To assess the impact of post-randomization changes in metformin use, two sensitivity analyses were conducted for the CV outcomes: (1) censoring for initiation and discontinuation of metformin during the study using the Cox proportional hazards model described above

2.1 Inclusion criteria We defined strict inclusion criteria to select which functional food active ingredients and studies to include in this review

The personal impact on staff