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The latter phosphorylates phosphorylase kinase, which further phosphorylates low-active phosphorylase b converting it to highly active phosphorylase a

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Consequently, targeted combinations of symbiotic bacteria may enhance the intestinal microbial composition, attenuate renal tissue injury, and improve kidney function indicators in AKI

Additional signs may include elevated creatine phosphokinase, myoglobinuria (rhabdomyolysis), and acute renal failure

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[10] [11] Eligibility is assessed on an individual basis by a clinician in line with NICE guidance