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PMCID: PMC8978023

234 MTAP is located in the periphery of the tumor suppressor cyclin-dependent kinase inhibitor 2 A (CDNK2A), and the co-deletion of the two genes occurs in ~15% of cancers and results in a highly aggressive tumor with a poor prognosis

To view the full article visit: OBJECTIVE OF THE RESEARCH Sustained hyperglycemia is associated with low cellular levels of the antioxidant glutathione (GSH), which leads to tissue damage attributed to oxidative stress

The study demonstrates that in the context of this specific dietary model of NASH, n-3 PUFA administration promoted a more severe inflammatory phenotype, contrary to the anti-inflammatory effects often observed in other metabolic contexts

Dimpfel W, Suter A

It's also worth emphasizing that you aren't alone in this process