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Prohaska JR

Additionally, the expression of mRNA and protein for both 25-hydroxylases (CYP2R1 and CYP27A1), 1--hydroxylase (CYP27B1), and VDR were downregulated, but that of 24-hydroxylase (CYP24A1) was significantly upregulated in the liver of HFD-fed mice compared to those in controls (Fig

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The activation of the JAKSTAT signaling pathway was suppressed by overexpressing aquaporin 1, indicating that aquaporin 1 improves aging and ageassociated dysfunction in TSPC by blocking the JAKSTAT signaling pathway [109]

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