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When applied as a cream, glutathione acts only superficially, as the glutathione molecule is too large to penetrate the skin barrier in significant amounts

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If you dont experience side effects within the first week, you can gradually increase your dose at your own pace: Start with 0.2mg (8 units) your first week Increase by 0.02mg (1 unit) per week if theres no side effects Dont exceed 0.4mg (16 units) per week For example, if you dont experience side effects on 0.2mg (8 units) per week, you can slowly increase your dose at a rate of 0.02mg (1 unit) per week, until you reach 0.4mg (16 units)