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Clinical obesity 9(4):e12323 Jensterle M et al (2022) Efficacy of GLP-1 RA approved for weight management in patients with or without diabetes: a narrative review

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GLP-1s appear to stand alone in producing results like that across all substances at once

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Consider contacting your prescriber if: diarrhea persists beyond 4 weeks at a stable dose, you are losing more than 3% of body weight per week, you cannot maintain adequate nutrition or hydration, or OTC management fails to provide relief