Lower doses typically provide less appetite suppression and result in slower weight loss
Here is how the muscle-preservation options compare for someone on a GLP-1: From YourHealthier: our Creatine Hydration Powder pairs creatine monohydrate with a hydration base, which is convenient on a GLP-1 because hydration is its own challenge when you are drinking and eating less (more on that below)
S., Ortiz-Prado, E., Rico-Fontalvo, J., Gmez-Mesa, J.-E., Abreu-Lomba, A, & Rivera-Martnez, W.-A
The tradeoff is that more receptors also means more side effects, especially nausea and (for retatrutide) unusual skin sensations
Estrogen may amplify GLP-1s effect
Cost Offsets: Studies suggest GLP-1 medications can reduce healthcare costs for diabetes-related complications by 20%30% annually per member