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All procedures were approved by the Animal Care and Use Committee of Hubei University of Science and Technology, Xianning, China (IACUC Number: 2021-03-003)

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GLP-1 use has also been linked to a lower risk of developing 14 obesity-related cancers, suggesting a potential preventative effect 3

Then, the [2,3]-sigmatropic rearrangement of INT1-S via TS1-S forms an ortho -S = N substituted dearomatized species INT2-S , with a barrier of 9.7 kcal mol 1