The tripeptide exists intracellularly either in an oxidised glutathione disulphide (GSSG) or reduced state (GSH), and maintaining an optimal GSH:GSSG ratio in the cell is critical for prevention of oxidative damage and for cell survival (Fig
Dysregulated calcium fluxes promote malignant progression by disrupting cell cycle regulation, inhibiting apoptosis, and facilitating epithelial-mesenchymal transition (EMT) and cytoskeletal remodeling [23-27]
This article summarizes representative studies from each wave with attribution and methodology context
This crosstalk leads to cytoskeletal destabilization under oxidative stress
Monatshefte Fr Chemie / Chemical Monthly 2005 136:8, 136(8), 13831390
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