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What Happens If You Stop Taking GLP-1 Medications Discontinuing GLP-1 therapy does not cause harm, but weight regain is common when treatment ends without lifestyle modification support

Splitting the weekly dose into two smaller injections is sometimes done to reduce peak drug concentration and minimize GI side effects

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P., Walkowiak, J., Herzig, K.H., & Raza, G.S

Macroalbuminuria occurred less (2.2%) in exenatide group compared to placebo group (2.5%) [HR 0.87 (95% CI: 0.701.07)]

In the new retrospective cohort study, researchers from the Cleveland Clinic analyzed electronic health record data from 7,938 adults with overweight or obesity who began injectable semaglutide or tirzepatide between 2021 and 2023