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Inflammation and Gut-Brain Axis Link Obesity to Cognitive Dysfunction: Plausible Pharmacological Interventions

Neurodegeneration: redoxproteostasismitochondria triad Neurons operate close to an oxidative edge because they consume large amounts of O 2 , are enriched in polyunsaturated lipids that are easy substrates for peroxidation and rely on long axons studded with far-flung mitochondria that are hard to replace

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Aging, as well as viruses, bacteria, poor diet, and certain medications, can deplete glutathione, resulting in impaired immune function and oxidation defense

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