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At the same time, the complex regulation of skin pigmentation is much better understood with increased knowledge on the physiopathology of pigmentary disorders, beyond the sole melanogenesis, including the whole tissue environment of melanocytes

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A reduced number of -H2AX foci as well as a reduced number of MLH3 were detected at all the prophase stages that were observed, drawing the conclusion that in dsyCS mutants the formation of double strand breaks were impaired