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Appearance of large scavenger receptor A-positive cells and increased small scavenger receptor A positive cells in peripheral blood is associated with mortality in systemic inflammatory response syndrome and multiple organ dysfunction syndrome

10.1177/17562848251347347 471 WangQ.-J.ShenY.-E.WangX.FuS.ZhangX.ZhangY.-N.et al

From experimental data of kinetic measurements of BRET, following vehicle and baseline corrections, quantification of induced responses from individual peptide concentrations was determined by calculating the net area under curve from the 10 min response (AUC 0-10min) ) in GraphPad Prism version 9.0.1 (GraphPad Software Inc., San Diego, CA)

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(72) showed that LPS increases intestinal permeability via induction of expression of TLR4 and CD14 in enterocytes, an event that is mechanistically related to destabilization of tight junctions