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Trial evidence for tirzepatide Tirzepatide's weight-management evidence comes chiefly from the SURMOUNT program, published in The New England Journal of Medicine in 2022, with SURMOUNT-OSA extending to obstructive sleep apnea in 2024

doi: 10.1152/ajpgi.00076.2012 22 HellstrmPNslundEEdholmTSchmidtPKristensenJTheodorssonEet al

If you experience insomnia while taking Semaglutide, its important to discuss this with your healthcare provider

The Phase 2 clinical trial showed approximately 2-3 kg of additional fat loss compared to placebo over 12 weeks

Patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN 2), patients with severe gastrointestinal disease, and pregnant patients should not take tirzepatide

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