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Suh SW, Won SJ, Hamby AM, Yoo BH, Fan Y, Sheline CT, et al

In 1965, Abbott Laboratories first patented this analog and marketed it as tramiprosate

Real-world effectiveness Studies examining real-world outcomes show that results are typically somewhat lower than in clinical trials but still significant: A 2025 Cleveland Clinic study found average weight loss of 10-15% in routine clinical practice (compared to 15-22% in trials)

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Incorporate a variety of fruits, vegetables, and whole grains into your daily diet