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Headaches accompanied by fever and neck stiffness need urgent evaluation

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Metabolism 29:369, 1980

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ILC2, group 2 innate lymphoid cells

It has been previously shown that 4-keto-VPA causes abnormal and irregular growth of the neural tube neuroepithelium, microvesicular steatosis, and reduces ammonia excretion through inhibition of carbamoyl phosphate [114], which significantly increases the risk of VPA-induced ADRs, including teratogenesis