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Figure 5 Preclinical or clinical development activity of the three candidate druggable genes for cataract was further evaluated (Table 3)

Selection Criteria: systematic review Inclusion criteria for the systematic review were the collection of neuroimaging (i.e., fMRI) data during exposure or reaction to reward-related stimuli in humans, combined with the measurement of endogenous levels of ghrelin or GLP-1 and/or administration of an exogenous GHS-R or GLP-1R agonist or antagonist

The molecule is verified against its published identifiers, including CAS 189691-06-3 and PubChem CID 9941379, so the material in the vial matches the compound described

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79 Notably, a high percentage of striatal DAT (at least 47%) needs to be occupied by cocaine in addicts before they report subjective effects of the drug, 80 implying that modulating DAT surface expression alters the reinforcing effects of cocaine in humans

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