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Lixisenatide, another GLP-1 analogue, has also been reported to decrease atheroma plaque size and instability in animal models, by reprogramming macrophages towards M2 phenotype (10 g/kg/day) (30)

Tirzepatide is available by prescription in Canada for diabetes and obesity

Clinical research and our own patient experiences show that most individuals see noticeable weight loss between four and eight weeks, with the most dramatic results often appearing after three to six months of consistent use combined with healthy lifestyle habits

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Qsymia works through central nervous system stimulation (phentermine) and neurotransmitter modulation (topiramate)

Efficacy and safety of tirzepatide in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized phase II/III trials