Despite its importance, 26.9% of people with diabetic foot ulcers are zinc deficient.[1] Clinical protocols often include zinc supplementation (220mg zinc sulfate three times daily for up to two weeks) with vitamin C.[7] Long-term high-dose supplementation requires medical supervision, as zinc can interfere with copper absorption and some diabetes medications.[12] Best zinc food sources: Oysters : 74mg per 3oz Beef and pork : 7mg per 3oz Chicken : 2.4mg per 3oz Pumpkin seeds : 2.2mg per ounce Cashews : 1.6mg per ounce Chickpeas and lentils : 1.3mg per half cup Animal sources provide more bioavailable zinc, but combining plant sources with vitamin C enhances absorption
doi: 10.1126/scitranslmed.3001006 80
The ongoing enhancement in the pharmacokinetic and pharmacodynamic characteristics of these drugs has led to their expansion of use beyond TD2 and obesity, including a decrease in cardiovascular events (Ciardullo et al
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Sickle Cell Disease in Children and Adolescents: A Review of the Historical, Clinical, and Public Health Perspective of Sub-Saharan Africa and Beyond
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