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Evidence grade: mechanistically credible, clinically unproven

Beyond weight management, Semaglutide also targets type 2 diabetes, offering a comprehensive solution for improved health outcomes

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Indeed, an opposite approach, as the pulse feeding strategy, whereby ~ 80% of daily protein is consumed in a single meal, has been shown to improve nitrogen retention in older women and to enhance lean mass preservation in malnourished elderly patients [47]

Trial SURPASS-5 (JAMA 2022) Population 475 adults with T2D + insulin glargine