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But, talk to your doctor about side effects

By blocking NNMT, it prevents the methylation and disposal of nicotinamide, raising intracellular NAD+ levels and activating SIRT1-mediated fat oxidation

Allergic reactions: An allergic or irritating reaction is your body's immunological response to a material that it perceives as threatening

Opiates panel : Quinolone antibiotics (ciprofloxacin, levofloxacin) and poppy seed consumption can cause false positive results, though modern federal testing uses higher cutoffs that reduce poppy seed interference

In fact, during Hersheys Q1 2026 earnings call, the companys CEO reported that sales of Ice Breakers mints and gum increased more than 8%, attributing the rise in part to people taking GLP1 medications and trying to manage bad breath

It also appears to affect areas of the brain involved in appetite, making it easier for some patients to reduce portions and control cravings