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Investigations suggest that simultaneous engagement of these two pathways may create a coordinated signaling environment that could provide insight into how multiple regulatory signals converge within endocrine systems
221 The addition of L-citrulline (a precursor of the L-arginine cycle and NO synthesis) to medications in obese asthmatic patients may assist in asthma control and improve fractional NO excretion (FeNO) levels
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Thus, robust mitochondria = slow aging
The schematic in Figure 2C captures the sequential progression of hallmark AD features, such as amyloid plaques, tau tangles, neuronal loss, gliosis, synaptic degeneration, and cognitive decline
doi: 10.1038/s41598-021-86300-4 76 PoliniAMeleESciancaleporeAGGirardoSBiascoACamposeoAet al
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