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The magnesium, in particular, can help reduce the frequency and severity of headaches by promoting muscle relaxation

Triple-Hormone-Receptor Agonist Retatrutide for Obesity Phase 2, NEJM , 2023 ClinicalTrials.gov TRIUMPH-1 (NCT05929066), TRIUMPH-2 (NCT05929079), TRIUMPH-3 (NCT05882045), TRIUMPH-4 (NCT05931367) FDA Wegovy prescribing information, 2025 FDA Zepbound (tirzepatide) prescribing information, 2024 Medical disclaimer: This article is for informational purposes only

Understanding vial longevity is critical for both safety and getting full value from each purchase

The longer-term picture is timing-dependent, since started near menopause it appears cognitively safe and may track with lower dementia risk, and the FDA removed the boxed warning, including the probable-dementia language, in 2026

Hiersemenzel (1990)

Immune function: Important for immune cell function