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Additionally, paclitaxel-induced inflammation and oxidative damage can further exacerbate calcium dysregulation by affecting the calcium channels and pumps ( 9 White matter integrity changes White matter integrity refers to the structural soundness and organization of the brains white matter, which is composed of myelinated nerve fibers that connect various brain regions
This reduction directly impacts the synthesis of Insulin-like Growth Factor 1 (IGF-1) in the liver, leading to systemic changes in tissue repair, cellular regeneration, and metabolic efficiency
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Metformin activation of ampk suppresses age-induced inflammatory response in hnscs
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