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Rare but serious gastrointestinal complications have been reported in post-marketing surveillance, including: Acute pancreatitis : If suspected, the GLP-1 agonist should be stopped immediately and not restarted if pancreatitis is confirmed Severe gastroparesis : Rare post-marketing reports of severe delayed gastric emptying Intestinal obstruction : Very rare cases reported in post-marketing surveillance Patients should be advised to seek urgent medical help via NHS 111, A&E or 999 as appropriate if they experience severe or persistent abdominal pain, persistent vomiting, abdominal distension, inability to pass stool or gas, or bloody diarrhoea whilst taking GLP-1 agonists

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This occurred despite similar weight loss between groups

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Week 58:Hyperpigmentation reduced

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Mochi Health has also offered compounded semaglutide during periods of FDA-declared shortage, a practice the FDA has warned consumers about given quality-control risks at some 503A compounding pharmacies [1]

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(Bron: Diabetes Fonds, EenVandaag, Science, Thuisarts.nl, Apotheek.nl, De Tafel van Gert, 24Pharma.nl, Instituut Verantwoord Medicijngebruik, RTL Nieuws, De Volkskrant, NRC, Nederlandslank.nl

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