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Therapeutic strategies, including iron chelators, antioxidants, and lipid metabolism modulators, demonstrate efficacy in preclinical models by attenuating ferroptosis

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Additionally, if OCSCs are exposed to inflammatory mediators, undergo mesenchymal endothelial transformation, or experience dysregulation of the redox balance in the tumor microenvironment (TME), they may stimulate the continuous proliferation of OCSCs, potentially leading to OC development (63)

10.7150/thno.22679 87 ZhouR.WangH.YangY.ZhangC.DongX.DuJ.et al (2019)

Allow 2-4 weeks to assess tolerance before increasing

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