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Acknowledgments Figure was Created in Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Doctors often use intramuscular injections to deliver NAD+, but it is not the sole option available

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The peptide diffuses slowly from the injection site into surrounding capillaries over 3090 minutes, creating sustained low-level serum exposure rather than the sharp peak seen with intravenous bolus

dosing of semaglutide, estimated individual parameter values obtained from the oral model were compared to, and found to be in accordance with, the expected values from the s.c./i.v