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Fertility considerations and menstrual regularity: PMOS is one of the most common causes of infertility in those capable of pregnancy
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In L-cells of the lower intestine and colon the proprotein convertase subtilisin/kexin type 1 (or PCSK1/PC1) cleaves after single or double basic amino acids to liberate glicentin (amino acids 21-89 in proglucagon), oxyntomodulin (amino acids 53-89 in proglucagon), GLP-1 (amino acids 92-128 in proglucagon), and GLP-2 (amino acids 146-178 in proglucagon) (see UniProt P01275)
Effectiveness and tolerability of liraglutide as add-on treatment in patients with obesity and high-frequency or chronic migraine: a prospective pilot study
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