Its potential looks larger, but its long-term safety is unknown
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The cost-effectiveness depends on whether the additional weight loss translates to greater health improvements
Semaglutide with pyridoxine versus tirzepatide with B6 Tirzepatide (the active ingredient in brand-name Mounjaro and Zepbound) is a dual GIP/GLP-1 receptor agonist that has shown even greater weight loss efficacy than semaglutide in head-to-head trials
The data we currently have on cagrilintide alone come from a deeper follow-up analysis of a larger study called REDEFINE 1
However, while GLP-1 focuses primarily on glucose metabolism and appetite, GLP-2 has a completely different set of functions centered on intestinal health