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Microbiota-derived metabolites are key mediators of host-microbe interactions ( 2.3 Bidirectional neuroendocrine crosstalk In addition to regulating host metabolism and immune responses, the gut microbiota is recognized to play a critical role in the production of neurotransmitters and engages in complex bidirectional communication with the hypothalamicpituitarygonadal (HPG) axis, contributing significantly to the pathogenesis and potential treatment of PCOS

But that approach would need to be trialed and tested, McCoy says

GLP-1 receptors are found in the brain and the pancreas

It affects metabolism, hormone function, blood sugar regulation, and long-term health

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