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Due to the high prevalence of prediabetic hyperglycemia and diabetes mellitus (DM) in pancreatic cancer patients (over 75% in high glucose status and 50% in diabetic status), a peripheral increase of insulin level and exogenous insulin injection can often be seen in PDA cases (Korc, 2007

Pulchinenoside B4 exerts the protective effects against cisplatin-induced nephrotoxicity through NF-B and MAPK mediated apoptosis signaling pathways in mice

308 These results suggest that the cardiac UPS cannot degrade excess ubiquitinated proteins because of overwork

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J Braz Chem Soc