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Pfizer also said that the placebo-adjusted reduction in mean body weight had ranged from -5% to -9.5% at 26 weeks and -8% to -13% at 32 weeks

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Not seeing results If you are on both HRT and a GLP-1 medication but not seeing expected results, several factors may be at play: Check hormone levels

3.2 Adipose tissue In humans, infusions of GIP(3-30)NH 2 during a hyperinsulinemic and hyperglycemic clamp reduce GIP-induced blood flow to subcutaneous adipose tissue and inhibit the increase in triacylglycerol clearance observed with GIP administration (22)