peter attia on semaglutide 246 - AMA #45: Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent Peter Attia: Our conversation about

Other oral antidiabetic medications, including SGLT2 inhibitors and DPP-4 inhibitors, are generally not recommended during breastfeeding due to limited safety data

The most common side effects of semaglutide and tirzepatide include: Nausea Vomiting Diarrhea Constipation Stomach Pain There can be serious side effects to both drugs as well, including: Pancreatitis Hypoglycemia Gallbladder Problems Allergic Reactions Kidney Failure Vision Changes If you are taking either of these medications and have a severe reaction, seek medical help immediately

Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population

Tirzepatide (Zepbound for weight loss, Mounjaro for diabetes), liraglutide (Saxenda), and older agents such as phentermine-topiramate (Qsymia) are also possibilities

They are also exploring whether related receptors, such as GIPR and GCGR, behave in a similar way in tissues like the liver and fat

Physiological roles of ketone bodies as substrates and signals in mammalian tissues