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Sleep architecture is also disrupted, with reduced Rapid Eye Movement (REM) sleep, increased awakenings, and poor sleep quality (99, 100)
A vial left on the counter for six hours might look identical but deliver 70% of its labelled dose per injection due to partial degradation
Management focuses on clinical responseimprovement in symptoms such as fatigue, cognitive function, and neurological signs
For instance, a common regimen for cognitive support might be 5 mg twice daily (10 mg/day) or 5 mg in the morning and 10 mg in the afternoon (15 mg/day) if tolerated and deemed necessary