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595,596 Recent studies have demonstrated that itaconate derivative 4-octyl itaconate (OI) also inhibits glycolysis and exerts anti-inflammatory effects by targeting glyceraldehyde 3-phosphate dehydrogenase (GAPDH)

Providers can assess individual risk factors, adjust diabetes management strategies accordingly, and provide personalized guidance

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PMID 2355952

While these compounded versions are not themselves FDA-approved, they are a common and legal way for patients to access necessary medications, especially during times of manufacturer shortages

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