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The groups that received the riboflavin-fortified salt had lower rates of esophageal cancer.[ref] Inflammatory Bowel Disease (IBD): In patients with Crohns disease, riboflavin (100mg/day) decreased inflammatory markers significantly in three weeks.[ref] Related article: IBD and Genetic Connections Inflammation: A randomized, placebo-controlled trial of supplemental riboflavin found that it reduced inflammation based on a lower CRP level.[ref] Related article : Inflammation and chronic disease Gut microbiome interactions with riboflavin: Certain gut microbes can produce riboflavin, part of which is then absorbed into the body

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Precision in dosing affects three critical outcomes

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Int J Drug Dev Res 3 Narang N, Sharma J (2011) Sublingual mucosa as a route for systemic drug delivery