In fact, it has been reported that some mice die even though they retain 70% of their hepatocytes [37]
However, the most important advantage is the very safe profile of BPC (the lethal dose (LD1) could be not achieved) (Seiwerth et al., 2018), emphasized in terms of its physiological role (assessed using in situ hybridization and immunostaining for BPC 157 in the human gastrointestinal mucosa, lung bronchial epithelium, the epidermal layer of the skin, and kidney glomeruli) (Seiwerth et al., 2018)
Some have stricter controls
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It can be coordinated by transcription factors (such as Nrf2) and amino acid transport systems
This approach captures both the protective daytime benefits and the regenerative nighttime benefits