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In parallel, metabolic modulators such as metformin, dapagliflozin, and glucagon-like peptide-1 receptor agonists reprogram ovarian bioenergetics by reshaping substrate utilization, suppressing inflammatory and oxidative signaling, and improving mitochondrial efficiency within the ovary
Elevated levels of serum glutamic pyruvic transaminase (SGPT, also as known as ALT), serum glutamic oxaloacetic transaminase (SGOT, also known as AST), urine albumin, and albumin/creatinine ratio were also noted, indicating potentially poorer kidney and liver function
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After -oxidation, butyrate will eventually produce two molecules of acetyl-CoA [21], whose concentration directly affects the level of protein acetylation
