NICE recommends PDE5 inhibitors (sildenafil, tadalafil) as first-line ED treatment, with success rates of 60-70% and well-characterised safety profiles
Whilst B12 injections (hydroxocobalamin) are licensed NHS medicines for treating confirmed deficiency states such as pernicious anaemia, lipotropic injections lack MHRA marketing authorisation and robust clinical evidence
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It controls processes that occur inside the body, including protein synthesis, blood production, and cell division
Injecting slowly, using a new needle for every injection, and not rubbing the site after injection all reduce local reactions
Finally, poor oral bioavailability, incomplete toxicology, uncertain long-term effects, and the absence of controlled human trials remain major limitations