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Older adults lose muscle mass faster under caloric restriction

Oprah Winfrey has been turning heads this year after revealing that shes lost nearly 50 lbs (22.7kg) through a combination of fitness, lifestyle changes and an undisclosed type of GLP-1 medication

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This titration schedule helps minimise gastrointestinal side effects, which are the most commonly reported adverse reactions

The journey began in the 1980s with research on Gila monster venom, culminating in the discovery of exendin-4, a stable, effective peptide for treating diabetes, demonstrating the progression from initial discovery to blockbuster diabetes medications

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