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Ewenczyk A, Ziplow J, Tong M, Le T, de la Monte SM (2012) Sustained impairments in brain insulin/IGF signaling in adolescent rats subjected to binge alcohol exposures during development

(4) reported that an 8-week UA intervention led to a significant reduction in pain responses in a murine model of osteoarthritis

Conversely, no significant differences in type 2 inflammatory markers were observed between treatment with a GLP-1R/GIPR dual agonist and single GLP-1R or GIPR agonists [189]