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After a dose-titration and dose-stable run-in period of up to 16 weeks and a 2-week placebo run-in period, patients with inadequate glycemic control (A1C 7.5% to 10.5%) were randomized to the addition of either 100 mg of sitagliptin or placebo, administered once daily

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Patients with PlexusDx genetic context can discuss their predispositions with their provider, potentially allowing for more tailored dose adjustments, realistic side-effect expectations, and clearer therapeutic endpointsmoving beyond one-size-fits-all dosing toward precision treatment planning

Lancet 387 , 13771396 (2016)

By indication, the obesity and weight management segment held a 28% share of the market in 2025 and is expected to grow at the fastest CAGR of 18.6% during the projection period