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The postoperative perfusion in renal tissue is reduced, and the compensatory blood volume in the kidney is increased, which dilates the entering arterioles and constricts the exiting arterioles, thereby maintaining glomerular filtration, leading to renal medullary ischemia and triggering AKI

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These could include other classes of medications or focusing more intensively on lifestyle interventions

Resources [1] Kalra A, Yetiskul E, Wehrle CJ, Tuma F